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How does protein processing and secretion in a human cell happens? A vesicle forms from the rough endoplasmic reticulum, and the substances made by the er are transported by the vesicles within the cell. the vesicle then fuses with the golgi body and releases the substances into it, where the substances may be modified in the golgi body. secretory vesicles containing the modified substances are then pinched off from the golgi body, and these secretory vesicles fuse with the cell membrane and rel
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