Complement System Made Easy- Immunology- Classical Alternate & Lectin pathway
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Complement System Made Easy- Immunology- Classical Alternate & Lectin pathway
The complement system is a part of the immune system that enhances (complements) the ability of antibodies and phagocytic cells to clear microbes and damaged cells from an organism, promotes inflammation, and attacks the pathogen's plasma membrane.
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SOLVED:Discuss the differences between the alternative and classical pathways of complement activation.
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✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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Study Smarter with MedSchoolBro on Instagram: "Code HAVIC @medschoolbro = Mystery Discount Complement System: 30-sec Review 🛣 Three pathways lead to complement activation: • Classical pathway activated by IgG or IgM • Alternative pathway activated by microbial surfaces • Lectin pathway activated by mannose on microbes 🌀 C3 convertase produces C3a and C3b. 🔥 C5 convertase produces C5a and C5b. 💥 MAC (C5b–C9) forms pores that destroy microbes, especially Neisseria. 🔑 Key functions: • C3a and
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Study Smarter with MedSchoolBro on Instagram: "Code HAVIC @medschoolbro = Mystery Discount Complement System: 30-sec Review 🛣 Three pathways lead to complement activation: • Classical pathway activated by IgG or IgM • Alternative pathway activated by microbial surfaces • Lectin pathway activated by mannose on microbes 🌀 C3 convertase produces C3a and C3b. 🔥 C5 convertase produces C5a and C5b. 💥 MAC (C5b–C9) forms pores that destroy microbes, especially Neisseria. 🔑 Key functions: • C3a and
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✨Complement Coagulation Pathway✨ 🔸Interconnection between two major plasma cascade systems in the body: the Complement system (innate immunity) and the Coagulation system (blood clotting). 💐Complement Pathway💐 3 activation routes, all converging at the formation of C3 convertase → C5 convertase → Membrane Attack Complex (MAC, C5b–9): 🔸1.Classical pathway → triggered by Ag–Ab complexes (IgG, IgM) 🔸2.Lectin pathway → triggered by Mannose-binding lectin (MBL) 🔸3.Alternative pathway → triggere
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Study Smarter with MedSchoolBro on Instagram: "Code HAVIC @medschoolbro = Mystery Discount Complement System: 30-sec Review 🛣 Three pathways lead to complement activation: • Classical pathway activated by IgG or IgM • Alternative pathway activated by microbial surfaces • Lectin pathway activated by mannose on microbes 🌀 C3 convertase produces C3a and C3b. 🔥 C5 convertase produces C5a and C5b. 💥 MAC (C5b–C9) forms pores that destroy microbes, especially Neisseria. 🔑 Key functions: • C3a and
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