Heart failure is a heterogeneous syndrome. Approximately 30–50% of patients with heart failure have normal or near normal left ventricle function. Several epidemiological studies confirm that the ...

Heart failure (HF) with preserved ejection fraction (HFpEF) is a complex and increasingly prevalent syndrome, representing nearly half of all HF cases. Characterized by symptoms of HF despite a normal ...

The therapeutic efficacy of the cardiac glycoside digitoxin in patients with heart failure and reduced ejection fraction is not established. In this international, double-blind, placebo-controlled ...