The identification of subgroups of patients from randomized clinical trials that are of specific interest for guiding clinical decisions can be an attractive idea; however, since such trials are ...

Objective To investigate the credibility of authors’ claims of subgroup effects using a representative sample of recently published randomised controlled trials. Design Systematic review. Data source ...

When conducting clinical trials, investigators examine the effect of interventions on outcomes in the study population and often in subgroups of patients defined by baseline characteristics (e.g., ...

Efforts to improve reporting clinical trial results have led to the development of guidelines such as those recommended by the CONSORT group. 3,4 Transparent and comprehensive reporting of subgroup ...

1 Global Health Unit, Norwegian Knowledge Centre for the Health Services, N-0130 Oslo, Norway The extent to which the consistency of subgroup findings across trials can be assessed is limited by ...

Genetic and other host characteristics that have the potential to influence susceptibility to disease occurrence may exert that influence only in the presence of one or more environmental (or other ...

This example illustrates how to compute and display control limits for the maximum of a subgroup sample. Subgroup samples of 20 metal braces are collected daily, and the lengths of the braces are ...