Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Inside living cells, mitochondria divide, lysosomes travel, and synaptic vesicles pulse—all in three dimensions (3Ds) and constant motion. Capturing these events with clarity is vital not just for ...

Top: Random Illumination Microscopy (RIM) utilizes random speckle patterns to achieve super-resolution imaging of biological tissues, improving resolution by a factor of two compared to the optical ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

News Medical talks to Samuel Penwell and Winfried Wiegraebe about how the Vutara VXL enables robust, high-throughput 3D super-resolution via single-molecule localization, pairing bi-plane detection ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Researchers enhanced Stimulated Emission Depletion (STED) microscopy by replacing traditional fluorophores with nanographenes, enabling the observation of longer-duration processes, overcoming a ...