When designing a randomized experiment, some treatment allocations are better than others for answering the causal question we want to answer, i.e. will lead to less biased, more precise treatment ...
Complete randomization could result in an undesirable imbalance in the number of patients assigned to each treatment, especially in small trials. Therefore, a variety of restricted randomization ...
Restricted Randomization Methods With Maximum Tolerated Imbalance When a stratified permuted block design is applied in a sequentially enrolling multicenter clinical trial, at a given timepoint (such ...
Randomization is an important part of clinical trials. Using permuted-block randomization for forcing equal group sizes potentially harms the unpredictability of treatment assignments. This can allow ...
While randomization leads to balanced covariates and group size on average, in individual trials there can be substantial imbalances that compromise power and interpretability. The need to proactively ...
using StatsPlots #Tested with version v0.14.34 using Distributions #Tested with version v0.23.12 using GLM #Tested with version 1.8.0 using OrderedCollections #Tested with version 1.4.1 ...
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