A single enzyme that can generate all four nucleotide triphosphates, the building blocks of ribonucleic acid (RNA), was ...

In biology, enzymes have evolved over millions of years to drive chemical reactions. Scientists have now derived universal rules to enable the de novo design of optimal enzymes. As an example, they ...

Chemists created an enzyme with boronic acid at its reactive center. This approach can produce more selective reactions with boron, and allows the use of directed evolution to improve its catalytic ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...

Enzymes are amazing catalysts. These proteins are made of nothing more than a handful of Earth-abundant elements, and they promote a vast array of reactions, convert chemical energy to physical motion ...

Effective protein engineering can give us control over the generated products inside a cell. However, for many of the biochemical reactions responsible for these products, we don't we don't know the ...