The complement system is known to play critical roles in pathogen identification, initiation of innate immune responses and facilitation of adaptive immune responses. Several studies have suggested ...
Abstract—There is increasing evidence that complement activation may play a role in atherogenesis. Complement proteins have been demonstrated to be present in early atherosclerotic lesions of animals ...
Leptospirosis is a zoonosis caused by spirochetes from the genus Leptospira. This disease is common in tropical and subtropical areas, constituting a serious public health problem. Pathogenic ...
Abstract There is substantial evidence that activated components of the complement cascade are present in atherosclerotic lesions, and it was suggested some years ago that smooth muscle cells may be ...
The complement system is part of innate immunity and is comprised of an intricate network of proteins that are vital for host defense and host homeostasis. A distinct mechanism by which complement ...
1 Department of Pharmaceutical Sciences, College of Pharmacy, Texas A&M University, Kingsville, TX, United States 2 Department of Pharmacy Practice, College of Pharmacy, Texas A&M University, ...
The majority of patients with CIDP had extensive terminal complement complex C5b-9 deposition on endoneurial capillaries in sural nerve biopsies. The complement system seems to play a role in chronic ...
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