A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

タンパク質合成に重要な役割を担うtRNAに糖（ガラクトースおよびマンノース）を付加する酵素を2種類同定しました。 tRNAの糖付加修飾は適切な翻訳速度の調節を担うこと、またその分子基盤を明らかにしました。 これらのtRNA修飾の欠損はタンパク質 ...

病気の変異を持ったままでも光明が見えてきた —— tRNA 修飾酵素でミトコンドリア病の治療を目指す —— [発表のポイント] 細胞中のごく微量なミトコンドリア tRNA中の化学修飾塩基を高感度に検出・定量する方法を開発しまた。 ミトコンドリア ...

The research group led by Professor Tsutomu Suzuki of The University of Tokyo is opening new horizons in RNA modification research. In particular, the group has discovered a reversible RNA ...

Kumamoto [Japan] September 30 (ANI): A pioneering study undertaken by a Kumamoto University research team shed light on the crucial role of TRMT10A, a tRNA methylation enzyme, in sustaining brain ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Boston, Massachusetts--(Newsfile Corp. - April 29, 2025) - Tevard Biosciences, Inc., a privately held biotechnology company pioneering tRNA-based therapies to cure a broad range of genetic diseases, ...

Researchers say discoveries could expand the CRISPR toolbox and lead to more efficient, rapid diagnostic tools for detecting COVID-19, influenza, and RSV.

Researchers uncovered a previously unknown CRISPR immune response in bacteria that targets transfer RNAs. The newly ...