Fractures play an important role as flow paths in porous media. When an undersaturated reactive fluid is flowing in a fracture, the dissolution process will alter the flow paths locally. Dissolution ...
The aim of this study was to probe the dissolution mechanisms of amorphous solid dispersions (ASDs) of a poorly water-soluble drug formulated with a hydrophilic polymer. Ritonavir (RTV) and ...
Dissolution studies were carried out under nonsink conditions, and solution phase behavior was characterized using several orthogonal techniques. It was found that liquid–liquid phase separation (LLPS ...
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