One of the challenges faced when developing influenza virus vaccines is the problem of how to protect populations in the face of spreading pandemics. With the advent of air travel, this readily ...

To evaluate whether the fusion of C3d increases the ability of Env trimers to engage mouse B cells through C3d and CR2 interaction, we labeled JRFL and fusion JRFL-C3d trimers with Alexa Fluor 680 dye ...

The alternative pathway of complement is important in innate immunity, attacking not only microbes but all unprotected biological surfaces through powerful amplification. It is unresolved how host and ...

Tumors are immunogenic in part because of somatic mutations that originate novel peptides that once presented on MHC engage cell-mediated immunity (CMI). However, in spite of the higher mutation load ...

Cleavage of C3 to C3a and C3b plays a central role in the generation of complement-mediated defences. Although the thioester-mediated surface deposition of C3b has been well-studied, fluid phase ...

C3D GAMESは、オープンワールド戦略RPG『Crown and Adventure』の正式版を10月23日にSteamでリリースするとの予告を行った。 本作は、Steamの体験版で高い評価を得ており、Steam戦争ゲームフェス体験版ランキング1位、4Xゲームフェス体験版ランキング2位を獲得している。

Background We have developed imaging probes for detecting C3d deposits in the kidneys and other tissues. After immune-complexes deposit in the glomeruli of patients with lupus nephritis (LN) and other ...

† Department of Bioengineering, University of California, Riverside, California 92521, United States ‡ Department of Chemistry and Biochemistry, University of California, San Diego, California 92093, ...