Transposable elements are DNA sequences which are also known as “jumping genes”, given their ability to move from one location of the genome to another. They are present in all eukaryotic genomes and ...

Heterochromatin, sometimes known as the “dark side of the genome,” is a poorly studied fraction of DNA that makes up about half of our genetic material. For more than 50 years scientists have puzzled ...

In healthy cells, transposable elements (TEs) are typically inactivated by methylation. But in cancer cells, these elements can become demethylated, enabling them to be expressed (1). Some ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the 'dark side' of the ...

To understand how organisms are related, researchers use molecular information to construct phylogenetic trees. Most of the time, scientists use thousands of protein-coding sequences to determine ...

Sankey diagram illustrating the inferred functions of TE-proximal genes. The width of connections between each vertical block represents the gene count, delineating GO term classifications associated ...

This schematic illustrates how transposable elements, derived from functional RNAs or retroviruses, shape the human genome and act as regulatory DNA elements. It highlights their essential roles in ...

New research findings pertaining to transposable elements, also known as jumping genes or mobile elements, increase our understanding of how cancers develop. Nearly half of the human genome is ...