The discovery in maize of jumping genes, also known as transposable elements, revolutionised our perception of genome organisation across kingdoms. Transposable elements are mobile small repetitive ...

In healthy cells, transposable elements (TEs) are typically inactivated by methylation. But in cancer cells, these elements can become demethylated, enabling them to be expressed (1). Some ...

To understand how organisms are related, researchers use molecular information to construct phylogenetic trees. Most of the time, scientists use thousands of protein-coding sequences to determine ...

Sankey diagram illustrating the inferred functions of TE-proximal genes. The width of connections between each vertical block represents the gene count, delineating GO term classifications associated ...

Over half of our genomes consists of thousands of remnants of ancient viral DNA, known as transposable elements, which are widespread across the tree of life. Once dismissed as the 'dark side' of the ...

This schematic illustrates how transposable elements, derived from functional RNAs or retroviruses, shape the human genome and act as regulatory DNA elements. It highlights their essential roles in ...

New evidence suggests a mechanism by which progressive accumulation of Tau protein in brain cells may lead to Alzheimer’s disease. Scientists studied more than 600 human brains and fruit fly models of ...

New research findings pertaining to transposable elements, also known as jumping genes or mobile elements, increase our understanding of how cancers develop. Nearly half of the human genome is ...

Researchers from the University of New South Wales (UNSW) Sydney report they have discovered that a particular transposable element in the genome has an effect on the immune response to virus ...