The identification of subgroups of patients from randomized clinical trials that are of specific interest for guiding clinical decisions can be an attractive idea; however, since such trials are ...

3 Department of Internal Medicine, University of Michigan School of Medicine 4 Department of Internal Medicine, Tufts University School of Medicine, Boston, MA, USA 5 Predictive Analytics and ...

2 Center for Clinical Epidemiology and Evidence-Based Medicine, West China Hospital, Sichuan University, Chengdu, China 3 Basel Institute for Clinical Epidemiology and Biostatistics, University ...

We review Bayesian and Bayesian decision theoretic approaches to subgroup analysis and applications to subgroup-based adaptive clinical trial designs. Subgroup analysis refers to inference about ...

Efforts to improve reporting clinical trial results have led to the development of guidelines such as those recommended by the CONSORT group. 3,4 Transparent and comprehensive reporting of subgroup ...

This example illustrates how to compute and display control limits for the maximum of a subgroup sample. Subgroup samples of 20 metal braces are collected daily, and the lengths of the braces are ...