PharmTech

Solid Dispersions by Hot-Melt Extrusion

The advantages and disadvantages of hot-melt extrusion in solid dispersion formulations. Solid dispersions represent a promising formulation approach for overcoming today's major challenge in ...
C&EN

Rheology Guided Rational Selection of Processing Temperature To Prepare Copovidone–Nifedipine Amorphous Solid Dispersions via Hot Melt Extrusion (HME)

*Address: Merck Research Laboratories, Merck & Co., Inc., WP75B-310 770 Sumneytown Pike, West Point, PA 19486. E-mail: [email protected]. Phone: (215) 652-0242 ...
Frontiers

Optimization of the Indirect Extrusion Process of Copper-Clad Aluminum Rods by Methods of Statistical Experimental Designs and Numerical Analyses

The success of composite extrusion is influenced by multiple process parameters. In order to investigate the significance of specific parameters during indirect extrusion of copper-clad aluminum (CCA) ...
SciELO

Crack Propagation Analysis of Magnesium Rod Processed by Extrusion-shear: Numerical Modeling and Experimental Verification

During extrusion-shear (ES) process, the surface cracks would be formed in the processed rod for AZ31 magnesium caused by nonhomogeneous metal flow and stress. To reduce the cracks defects, ...