Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Even those who maintain that super-resolution microscopy is a powerful tool of biological discovery have admitted that it may have a bit of an image problem. For example, in a recent review, several ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

Inside living cells, mitochondria divide, lysosomes travel, and synaptic vesicles pulse—all in three dimensions (3Ds) and constant motion. Capturing these events with clarity is vital not just for ...

Top: Random Illumination Microscopy (RIM) utilizes random speckle patterns to achieve super-resolution imaging of biological tissues, improving resolution by a factor of two compared to the optical ...

For human researchers, it takes many years of work to discover new super-resolution microscopy techniques. The number of possible optical configurations of a microscope -- for example, where to place ...

Example of super-resolution microscopy: The image shows how the Discrete Molecular Imaging (DMI) technology visualizes densely packed individual targets that are just 5 nanometer apart from each other ...

Immerse deeper and deeper into the inner world of cells with the microscope. Imaging the nucleus and other structures more and more accurately. Get the most detailed views of cellular multiprotein ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...