Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

This is a preview. Log in through your library . Abstract Since the availability of the first crystal structure of a bacterial Na⁺ channel in 2011, understanding selectivity across this family of ...

Do only potassium ions pass through the selectivity filter of a potassium channel, or are there water molecules between the ions? This question has been a source of controversy for years. Researchers ...

Researchers reveal how the presence of bulky aromatic amino acids at positions 1 and 3 of the aromatic/arginine selectivity filter determines urea and boric acid permeability in Aquaporin 10 paralogs.

Larger K+ (ionic radius: 1.3 Å) can selectively permeate larger Na + (ionic radius: 1.0 Å) through biological potassium ion channels, with selectivity ratios greater than 1000-fold. Scientists have ...