For the local signature management, this script needs to be run on a computer that has admin access to the remote workstations in order to edit the user AppData and the registry, preferably the Domain ...
I have a VBS script we use for Outlook Signatures. I had to rewrite it to work with 2016 as the new Terminal server has Office 2016 on it and in a few months we are moving away from Office 2010 by ...