DNA replication is a fundamental process essential for bacterial growth and survival. Initiation begins at the chromosomal origin (oriC), where the conserved initiator protein DnaA assembles into an ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing the entire repair sequence as it unfolds. Instead of freezing cells at ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as ...

This footage shows the fluorescent sensors in action inside a living cell. They appear as bright green spots the moment they bind to sites of DNA damage. Cancer research, drug safety testing and ...

A new LUMC study has changed our understanding of how cells work. Researchers have discovered that the CFAP20 protein acts as a kind of "traffic controller" on DNA. Without this protein, chaos ensues, ...