When we are interested in cause and effect relationships (which is much of the time!) we have two options: We can simply observe the world to identify associations between X and Y, or we can randomise ...

2 Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK 3 National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol NHS ...

Objectives To assess how often stratified randomisation is used, whether analysis adjusted for all balancing variables, and whether the method of randomisation was adequately reported, and to ...

Background Many observational studies highlight clonal haematopoiesis (CH) as a novel determinant of cardiovascular disease (CVD). However, disentangling cause and effect from important confounders, ...

Dublin, Ireland, 19th January, 2015 – ICON plc, (NASDAQ: ICLR) a global provider of drug development solutions and services to the pharmaceutical, biotechnology and medical device industries, today ...