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pythonnet-2.0-Beta0-clr4.0 cannot import clr from anywhere but C:\Python27 dir

I cannot import clr unless the 3 files (nPython, Python.Runtime & clr) are placed in the directory C:\Python27. If placed anywhere else I get the following error: "dynamic module not initialized ...
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pythonnet installation failed #1528

Pythonnet version: 2.5.2 Python version: 3.9.6 Operating System: Windows 10.NET Runtime: 5.0 NuGet.exe 4.1.0 en cours d'ex‚cution. Mise … jour de NuGet.exe vers 5.10.0. Mise … jour r‚ussie. MSBuild ...