A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

An international team of scientists have used advanced microscopy to image how ribosomes recruit to mRNA. Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell ...

Since mRNAs play a key role in protein synthesis in vivo, the use of mRNAs as medicines and for in vitro protein synthesis has been desired. In particular, mRNA therapeutics hold the potential for ...

The demand for the manufacturing of polypeptides has radically increased since the recent introduction of new diabetes, obesity and cardiovascular disease peptide drugs. Consequently, peptide API ...