Researchers developed ProtGPS, an AI tool that predicts protein localization in cells and how mutations affect disease. The model identifies functional disruptions and designs novel proteins for ...

Localizatome contains comprehensive information about the stress-induced protein localization changes within living cells. It provides open access to subcellular protein localization data through a ...

CAMBRIDGE, MA – A protein located in the wrong part of a cell can contribute to several diseases, such as Alzheimer’s, cystic fibrosis, and cancer. But there are about 70,000 different proteins and ...

Researchers developed a new machine learning method that, given a relevant amino acid sequence, can automatically predict the location of a protein in any human cell line down to the single-cell level ...

Subsequently, they employed a customized high-throughput microscopy system that included a plate transport robot. Live-cell fluorescence imaging was used to map the localization patterns of each ...