Manual patch clamping requires considerable skill and experience due to the technically challenging setup requirements, and as such, only allows recording of a small sample of cells (approximately ...

To record ion channel activity across cell membranes the conventional patch clamp remains the gold standard and is widely used in drug discovery research. However, this traditional method requires ...

Flip-the-Tip Technology Uses Standard Glass Pipettes to Achieve Higher Throughput in Ion Channel Screening The pharmaceutical industry has widely recognized patch clamping as the “gold standard” to ...

Dr. Kaneez Fatima Shad knows that the “Patch Clamp” method needs skills and patience. It takes the whole day to craft only one sample and even a small leak could alter the results drastically.

High-throughput screening (HTS) is a drug discovery strategy used extensively during early-stage pharmaceutical development. The patch-clamp technique remains the gold standard for testing the ...