To record ion channel activity across cell membranes the conventional patch clamp remains the gold standard and is widely used in drug discovery research. However, this traditional method requires ...

Scientists applied molecular dynamics simulations to visualize how potassium ions pass through a potassium ion channel at atomic resolution for the first time. (Nanowerk News) The patch clamp ...

The population patch clamp (PPC) technique measures a population of cells in parallel to mitigate the inherent biological variability seen when measuring from single cells. When a large enough ...

The patch clamp technique has revolutionized electrophysiological research and is applied in laboratories worldwide to date. It allows scientists to precisely measure the ion current through a single ...

The beating of a heart, the ability to learn and remember, and the movement of a sperm cell's tail all have at least one thing in common: They depend on the function of ion channels, the membrane ...