APL is a distinct subtype of myeloid leukaemia that in almost 100% of cases is associated with chromosomal translocations involving the PML and retinoic acid receptor α (RARA) loci, leading to the ...
Promyelocytic leukemia (PML) protein is a tumor suppressor implicated in tumorigenesis in different tissues. PML is object of intense research on the basis of this premise. A large number of ...
Promyelocytic leukemia protein (PML) nuclear bodies (NBs) are subnuclear domains proposed to facilitate posttranslational modifications. Among NB partners, proteins are p53 and are most of the ...
Promyelocytic leukemia Nuclear Bodies (PML NBs) are nuclear membrane-less organelles physically associated with chromatin underscoring their crucial role in genome function. The H3.3 histone chaperone ...
Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt, Germany Promyelocytic leukemia nuclear bodies (PML NBs) are multi-protein assemblies representing distinct sub-nuclear ...
Cancer Discov (2013) 3 (4): OF16. Upregulation of nuclear PML in glioblastoma confers resistance to mTOR-targeted therapies. Major finding: Upregulation of nuclear PML in glioblastoma confers ...
Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies
PML nuclear bodies (PML-NBs) are dynamic interchromosomal macromolecular complexes implicated in epigenetic regulation as well as antiviral defense. During herpesvirus infection, PML-NBs induce ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback