The events that enable polarization of T cells and migration across the vasculature to the target are largely unknown. New evidence suggests that PKC-β(I) may be pivotal in controlling this process.

In order to survive, cancer cells often rely on the protein kinase C epsilon (PKC-epsilon) signaling pathway to sort out tangled DNA that would otherwise trigger their destruction, according to a team ...

Over 13,000 articles published since 1966 seemed to show that all of these pieces of the puzzle were important in the pathogenesis of diabetic complications, yet two things suggested that something ...