M3

「PASIスコア」はこう使う！【エキスパート解説】

医師の臨床現場での判断をエビデンスに基づいて支援するm3.comのアプリ「臨床ポケット」では、様々な医療計算ツールやスコアを提供しています。本記事では、その中の一つ「PASIスコア」の使用において注意すべき点について専門家が解説します。 PASI ...
The American Journal of Managed Care

Is Using PASI 100 Realistic in a Real-Life Setting?

More real-world evidence is needed to determine what role a score of 100 on the Psoriasis Area and Severity Index (PASI) might have in daily clinical practice, according to a recent review. A score of ...
The American Journal of Managed Care

Decreased Efficacy, PASI Score vs BSA, and Nonresponders

The panel discusses the potential for decreased efficacy of treatment based on comorbidities. They also discuss the use of PASI score vs BSA to determine severity of disease and the need to identify ...
M3

乾癬への経口TYK2阻害薬zasocitinibでPASIスコア改善

中等度から重度の尋常性乾癬患者259例[18-70歳、乾癬面積・重症度指数（PASI）スコア12以上、医師の総合評価スコア3以上、乾癬の体表面積10％以上]を対象に、高選択的アロステリックチロシンキナーゼ2（TYK2）阻害薬zasocitinibの有効性、安全性、忍容性を第 ...
Medscape

Psoriasis Area and Severity Index Use in Pediatric Psoriasis

Psoriasis Area and Severity Index (PASI) score is the primary instrument used to assess psoriasis severity and determine eligibility for clinical trials. The PASI scoring system assumes fixed adult ...
Healio

Oral statins may improve PASI score in patients with severe psoriasis

Please provide your email address to receive an email when new articles are posted on . Statin use was associated with improvement in Psoriasis Area and Severity Index score among patients with severe ...
Medscape

TYK2 Inhibitor Promising for Moderate-to-Severe Psoriasis in Phase 3 Studies

DENVER — The selective tyrosine kinase 2 (TYK2) inhibitor envudeucitinib emerged superior to apremilast and placebo in two phase 3 trials of people with moderate-to-severe psoriasis. The oral TYK2 ...
National Institute for Health and Care Excellence

Ustekinumab for treating moderate to severe plaque psoriasis

is severe, as defined by a total Psoriasis Area Severity Index (PASI) score of 10 or more and a Dermatology Life Quality Index (DLQI) score of more than 10, and has not responded to conventional ...
Healio

Zasocitinib meets proof of concept in plaque psoriasis

Please provide your email address to receive an email when new articles are posted on . Patients treated with 15 mg and 30 mg of zasocitinib had significantly greater changes in mean PASI score ...