What are some significant markers that indicate we’re growing older? Wrinkles on our skin? — Yes. A grey streak or two? — Yes. The body’s pace of bounding back after a trying episode? — Double yes.

It has long been known that a hallmark of Alzheimer’s disease, and most other neurodegenerative diseases, is the clumping together of insoluble protein aggregates in the brain. During normal ...

You remember leaving something in the other room, and you move to get it. But when you pass through the doorway, all memory of what you went in to get vanishes, and you stand there empty handed, ...

While chronological age is easily measured, it fails to capture the complex biological processes that determine the rate of aging. A new proteomic aging clock may predict biological age, mortality ...

To date, approaches to treatments for Alzheimer's disease have not addressed the contribution of protein insolubility as a general phenomenon, instead focusing on one or two insoluble proteins.