Aging is the primary risk factor for numerous life-threatening diseases and has long been a central focus of biological research. Epigenetic reprogramming, a process that can modulate cell fate and ...

This figure shows primary T cells modified using two approaches. CAR receptors are introduced through targeted DNA insertion (top), while CRISPRoff mRNA and guide RNAs silence additional genes through ...

Germ cell development involves genome-wide epigenetic reprogramming, which occurs in a highly ordered fashion. Unveiling the mechanisms involved in this process would be important for understanding ...