Neural tube defects (NTDs) are severe congenital malformations affecting 1 in every 1000 pregnancies. 'Open' NTDs result from failure of primary neurulation as seen in anencephaly, myelomeningocele ...

Apoptotic cell death occurs in many tissues during embryonic development and appears to be essential for processes including digit formation and cardiac outflow tract remodeling. Studies in the chick ...

Spinal neural tube folding shows a transition from medial to dorsolateral neural plate bending sites (hinge points) along the embryo’s body axis. While hinge points are considered an important driving ...

Department of Developmental Neurobiology, Centre for Developmental Neurobiology and MRC Centre for Developmental Disorders, Institute of Psychiatry, Psychology & Neuroscience (IoPPN), King's College ...

Neural tube defects (NTD) are among the most frequent congenital malformations in humans. The current hypothesis is that they are of multifactorial origin due to the combined effects of sequence ...

The Hippo pathway, a highly conserved signaling cascade that functions as an integrator of molecular signals and biophysical states, ultimately impinges upon the transcription coactivator ...

You will be redirected to our submission process. The formation of the nervous system is a remarkable process that relies on the coordinated interplay of cellular programs, molecular signaling, and ...

Neural tube formation as embryo medical development stage outline diagram. Labeled educational scheme with convergence or crest stages and structure vector illustration. Primary neurulation process.