A study has described how a gene mutation linked to amyotrophic lateral sclerosis (ALS) disrupts the stability of neurons and “chokes off” their nuclei, impairing their function. The research, ...

In both of these neuro-degenerative diseases, aggregates of misfolded alpha-synuclein protein develop in brain neurons, including the hippocampus, the region of the brain that plays a vital role in ...

The transient receptor potential (TRP) ion channels comprise a diverse superfamily of cation channels that play pivotal roles in sensory transduction, enabling organisms to detect a wide range of ...