Overview: Xifyrm is a nonsteroidal anti-inflammatory drug (NSAID) that is given intravenously (IV) to treat moderate to severe pain. Constipation is the most commonly reported side effect. Xifyrm will ...

As with other drugs, ondansetron can cause side effects, such as fatigue, headache, and constipation. If side effects of ondansetron become difficult to tolerate, talk with your doctor or pharmacist.