Expensive computation in handling a large number of sequences limits the application of local multiple sequence alignment. We present an Eulerian path approach to local multiple alignment for DNA ...
With the rapid sequencing of many related genomes, comparative sequence analysis has emerged as one of the most important areas of computational biology. The fundamental tool of comparative sequence ...
Pairwise alignment class: Using the Needleman-Wunsch and Smith-Waterman algorithms, this project uses two classes to align two sequences of the same biotype (protein, R/DNA): a Substitution Matrix ...
In this paper, an approach is described that combines multiple structure alignments and multiple sequence alignments to generate sequence profiles for protein families. First, multiple sequence ...
1 Image and Signal Processing Group, Institute for Computer Science, Leipzig University, Leipzig, Germany 2 Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig, ...
This Perl module enables multiple sequence alignment of any base objects such as symbols, numbers or data structures. It is a considerably modified extension of Algorithm::NeedlemanWunsch pairwise ...