The field of regulated cell death has undergone a transformative shift with the discovery of novel modalities beyond apoptosis, such as ferroptosis, which ...

Hepatocellular carcinoma (HCC), characterized by high aggressiveness and recurrence, poses a significant global health challenge. The interplay between the tumour microenvironment and exogenous ...

A number of recent trials have explored potential strategies for using immunotherapy in chronic lymphocytic leukemia (CLL). The authors explained that while molecularly targeted therapies like Bruton ...

MILAN — Is chronic lymphocytic leukemia (CLL) progression primarily driven by genetic mutations or by external cues from the tumor microenvironment? Despite major strides in targeted therapies, CLL ...

Gastric and esophageal cancers rank among the deadliest cancers Worldwide, due to their biological complexity, late diagnosis, and limited response to ...

Cancer cells don’t exist in isolation – instead, they live within a complex ecosystem that also includes immune cells, stromal cells, the extracellular matrix, blood vessels and many other factors.

Cancer cells and tumors do not exist in a vacuum. Far from the isolation and self-sufficiency of the fictional Wakanda, tumors develop in and alter the nearby milieu of immune cells, connective tissue ...

Cancer remains a serious health threat within society, with 18 million new cancer cases occurring worldwide in 2020. While novel and more effective treatments continue to increase at a rapid rate, ...