Mendelian randomization is an approach to causal inference that uses genetic variants as instrumental variables to estimate causal effects of a risk factor on disease or health outcomes. Methods ...

The schematic illustrates the comprehensive pipeline for Mendelian randomization analysis, starting with multi-omics data inputs from GWAS, eQTL, and pQTL studies, sourced from major databases such as ...

A major goal of epidemiology is to reduce the burden of disease in populations through interventions that target causal determinants of disease risk. Although observational studies, such as ...