Global and genetic analyses link low physical activity to rising heart disease mortality, while higher activity levels appear ...

Mendelian randomization is not affected by the confounding inherent in observational studies but it does rely on several assumptions, which can be hard to test Mendelian randomization can provide a ...

1 College of Medical Information, Changchun University of Chinese Medicine, Changchun, China 2 College of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, China Background: ...

Although numerous Mendelian randomization studies on risk factors have been conducted in male medicine, a systematic synthesis of these findings is still lacking. This review searched relevant ...

The study presents valuable findings on Mendelian randomization-phenome-wide association, with BMI associated with health outcomes, and there is a focus on sex differences. The phenotype and genotype ...

Higher BMI and IBD causally increase hidradenitis suppurativa risk, large study finds, providing actionable insights for ...

Stroke is a leading cause of death worldwide, with a lack of effective treatments for improving the prognosis. The aim of the present study was to identify novel therapeutic targets for functional ...

Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...

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