Tandem mass spectrometry is a powerful tool in proteomics. By ionizing peptides and then fragmenting those ions into smaller product ions, researchers can determine the biomolecules’ amino acid ...

Effective protein characterization depends on the precise isolation and fragmentation of peptide ions within the mass spectrometer, typically coupled with liquid chromatography (LC-MS/MS). In a ...

For decades, mass spectrometry has been the gold standard in proteomics because of its combination of specificity, sensitivity, high target plex, and lack of requirement for affinity reagents. Yet, ...