NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

Plants, insects and mammals have a conserved innate immune system that is the first inducible defense against infectious disease, but the exact nature of the signaling molecules in this system remains ...

Researchers from Medical University Vienna presented data from a study that aimed to identify possible synergism between the novel son of sevenless (SOS) inhibitor BAY-293 and B-Raf or/and MEK1/2 ...

The Mitogen Activated Protein Kinase (MAPK) pathway is one of the most commonly mutated signalling pathways in human cancers. While a range of small molecule inhibitors have been developed to inhibit ...