University of Kentucky College of Medicine researchers were part of a new study that gives insight into how limb development evolved in vertebrates. The findings, published in Current Biology Oct. 4, ...

Human fingers and toes do not grow outward; instead, they form from within a larger foundational bud, as intervening cells recede to reveal the digits beneath. This is among many processes captured ...

Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.

Scientists have created a spatial atlas of the incredible process of human limb development, including steps that show digits emerging from a bud as cells recede, instead of growing outward. With ...

Scientists have shared unprecedented insights into human development with a world-first map that shows how limbs grow in the womb. Human fingers and toes do not grow outward; instead, they form from ...

This study is reported by Jia-Tang Li’s group from the Chengdu Institute of Biology, Chinese Academy of Sciences. The development of limbs is significant for the origin and evolution of tetrapods, ...

During early development, the embryo builds the body's organs by exchanging chemical signals between different cell types. When developing limbs, a thin band of skin cells at the limb’s surface, ...

Perhaps like a limb with multiple digits? The team will also try reintroducing the genes in tetrapod species, which normally lack the genes, to see how they affect limb development. "We will continue ...