Karl Fischer (KF) titration is a redox reaction which uses the consumption of water during the reaction to measure the amount of water in a sample. It is the reference method for water determination ...

This live and interactive online course provides an introduction to Karl Fischer Titration (KF), aimed at complete beginners. The course is also ideal for analysts or technicians looking for a ...

Karl Fischer discovered that if sulfur dioxide is added in the excess the same reaction can be used for water determination by titration of the produced acids. His base of choice was pyridine which ...

Most often, the presence of water in pharmaceutical substances, petroleum products, or foodstuffs is unwanted. For example, if water content is too high, it can reduce the shelf life of grains like ...

Pharmaceutical product quality, effectiveness and shelf life depends significantly on the water content in these products, which makes water determination in pharmaceutical analysis so important.

The authors developed a robust, automated system to conduct Karl Fischer moisture assays for lyophilized products. Karl Fischer titration is one of the few assay techniques recognized by the US Food ...

Karl Fischer (KF) titration has been used successfully to estimate water content in diverse samples for almost 90 years, dating back to 1935. 1 Image Credit ...