Ferulic acid suppresses ileal smooth muscle contraction by inhibiting calcium ion influx through voltage-dependent calcium channels. This action may help prevent or treat excessive intestinal motility ...

Some of the most intractable gastrointestinal disorders, such as irritable bowel syndrome and inflammatory bowel disease, are motility disorders, where the contents of the intestines don’t proceed ...

A study by scientists at Harvard Medical School and the Icahn School of Medicine at Mount Sinai has revealed how a pressure-sensitive protein, PIEZO1, helps regulate intestinal motility and control ...

A key pressure-sensing protein involved in intestinal movement and inflammation regulation has been identified. Researchers from Harvard Medical School (MA, USA) and the Icahn School of Medicine at ...

After every meal, the intestines perform an action called peristalsis - moving food through their hollow interiors with coordinated contractions and relaxations of the smooth muscle. For more than a ...

Maternal health and other events occurring during pregnancy determine the health outcomes in offspring. Pre-natal infections are a major risk factor contributing to compromised intestinal barrier ...

A research team led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Faculty of Pharmaceutical Sciences at Toho University has revealed that ferulic acid (FA), a ...