Learn how pH-sensitive dye detection supports reliable ADC internalization assays and insight into cellular uptake mechanisms ...

Here we used ‘late-phase’ imaging after challenge to test the hypothesis that D2R internalization is impaired in SZ. We used PET imaging with [11 C]raclopride in groups of patients with SZ and matched ...

Dye-based internalization detection reagents distinguish surface-bound from internalized ADCs to support drug optimization.

Hepatitis B virus (HBV) infects more than 250 million people worldwide and can lead to chronic liver disease and liver cancer. Current antiviral therapies suppress viral replication but do not ...

G protein-coupled receptors (GPCR) are a large and diverse class of plasma membrane receptors involved in transduction of extracellular signals. The range of GPCR ligands is broad and includes small ...

TORONTO, March 25, 2019 /CNW/ - Summit Industrial Income REIT ("Summit" or the "REIT") (TSX: SMU.UN) announced today that it has entered into an agreement (the "Purchase Agreement"), to internalize ...