Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, No. 22 (May 30, 2006), pp. 8528-8533 (6 pages) The maintenance of synaptic functions is essential for ...

Inositol trisphosphate receptors (IP3Rs) are pivotal Ca²⁺ channels embedded in the membrane of the endoplasmic reticulum. Their activation by inositol 1,4,5-trisphosphate (IP3) and Ca²⁺ gives rise to ...

Inositols are ancient molecules that were probably first made by a common ancestor of Archaea and Eukarya more than 2,000 million years ago. They are used by relatively few Bacteria.The ...

Inositol 1,4,5-trisphosphate receptors (IP₃Rs) initiate a diverse array of physiological responses by carefully orchestrating intracellular calcium (Ca2+) signals in response to various external cues.

Although it’s often referred to as vitamin B8, inositol is not a vitamin but rather a type of sugar with several important functions. It influences the action of insulin and may aid mental health and ...

Intracellular calcium signaling kicks into overdrive in Alzheimer’s disease neurons, but researchers do not know whether that causes the disease or is the result of it. Researchers from the University ...

In the evolving landscape of nutritional supplements, Inositol supplement has gained recognition among researchers and clinicians for its remarkable effects on hormonal and metabolic health. This ...

Choline and inositol are two essential nutrients that play critical roles in supporting overall health, particularly brain function and cellular structural integrity. While they’re often grouped with ...