MYC‑driven tumors silence innate immune alarms by clearing R‑loop–derived signals, exposing a new therapeutic angle for targeting MYC without broad inhibition.

The immune system can work in two ways: the innate immune system reacts to any foreign invaders that are identified by immune cells that look for such pathogens; but the acquired or adaptive immune ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

If you have had strep throat or an ear infection, there's a good chance you received amoxicillin or penicillin to effectively ...

Both autoimmune and autoinflammatory diseases (AIDs) are characterised by bouts of hyperactivation of immune reactions ...

Caenorhabditis elegans has emerged as a robust model for dissecting the fundamental mechanisms of innate immunity and host–pathogen interactions. Despite lacking an adaptive immune system, C. elegans ...

The BCG vaccine protects against tuberculosis, but by inducing trained immunity it also protects against many more respiratory infections. International research led by the Radboudumc shows how this ...