Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns. To advance ...

Around eight days after fertilization, the human embryo implants in the endometrium (the tissue that lines the uterus). After implantation, it enters a developmental phase that is not well understood ...

Two to three weeks after conception, an embryo faces a critical point in its development. In the stage known as gastrulation, the transformation of embryonic cells into specialized cells begins. This ...

In a new study, researchers compare the transcriptomic profiles of recently reported human embryo stage 8-cell-like cells with human embryos The onset of embryo-specific gene transcription, also known ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Cell compaction is a crucial step in embryo development. Defective compaction prevents the formation of the structure that ensures an embryo can implant in the uterus. This stage is carefully ...

Scientists have created synthetic human embryos using stem cells, in a groundbreaking advance that sidesteps the need for eggs or sperm. Scientists say these model embryos, which resemble those in the ...

The onset of embryo-specific gene transcription, also known as embryonic genome activation (EGA), is a crucial step in the developmental journey of an organism. Although EGA has been studied to some ...

A research team showed that, contrary to current models, one early embryonic cell dominates lineages that will become the fetus. “They are not identical,” said Magdalena Zernicka-Goetz, a ...

When Berna Sozen, PhD, assistant professor of Developmental Stem Cell Biology at Yale, was in her first weeks of pregnancy, she couldn’t help but wonder about what exactly was going on in the “black ...