Hot-melt extrusion offers many advantages compared with conventional solid dosage form manufacturing, and has consequently received considerable attention from both the pharmaceutical industry and ...

Continuous manufacturing has the potential to offer benefits in terms of reduced costs, footprint, raw material consumption, and byproduct and emission generation combined with increased process ...

The hot melt extrusion (HME) process can be employed in the production of a wide range of pharmaceutical dosage forms, including capsules, tablets, lozenges and implants. HME is suitable for both ...

Thanks to their safety, ease of application and ability to administer a precise dose of an active pharmaceutical ingredient (API), orally disintegrating films make an appealing method of dosage. The ...

Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid ...

Accurate prediction of breakthrough extruding force is very important for extrusion production, especially for the large-scale extrusion process, which directly affects the production costs and safety ...