ヒストンタンパク質は、外部からのさまざまなシグナルに応じて修飾されるが、その制御機構はまだ十分に解明されていない。シトルリン化は転写後修飾の1つで、タンパク質中のアルギニンがシトルリンに変換される。本論文では、DNA損傷に応じてヒストン ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...
In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...