It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

Gastrulation, a prerequisite for organogenesis, begins with the formation of the primitive streak (PS), where epiblast cells experience an epithelial-to-mesenchymal transition (EMT) to exit the ...

Scientists revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has implications for cell replacement ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

Scientists from Helmholtz Zentrum München revise the current textbook knowledge about gastrulation, the formation of the basic body plan during embryonic development. Their study in mice has ...

Due to ethical reasons and technical challenges, studying human post-implantation development has been limited. The closest that scientists have come to understand intrauterine development after ...

In vivo model systems are essential to study the various roles of this fascinating family of proteins in vertebrates. Among them, the zebrafish offers a number of advantages, for example, rapid ...

Gastrulation, the process where an embryo reorganizes itself from a hollow sphere into a multilayered structure, is considered a “black box” of human development. This is because human embryos are ...

In their publication in Science, Professor Guojun Sheng (Kumamoto University, Japan), Professor Alfonso Martinez Arias (Universidad Pompeu Fabra, Spain) and Professor Ann Sutherland (University of ...

Platelet-derived growth factor (PDGF) signaling is essential for processes involving cell motility and differentiation during embryonic development in a wide variety of organisms including the mouse, ...