GSH (glutathione) は活性酸素種の消去や還元力の提供など,細胞内で重要な役割を担うトリペプチドである.トリペプチドである GSH は構成アミノ酸三種が二回重合することで生じる.具体的に生合成経路は下記二段階から成る. Glu + Cys +ATP → γ-EC + ADP + Pi γ-EC ...
Glutathione (GSH) is depleted early in the course of Parkinson’s disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell ...
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