Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth. By ...
Natural "off switch" could slow or even reverse the growth of aggressive tumors. Cancer is the second leading cause of death in the U.S., claiming around 600,000 lives in 2022 alone. A diagnosis can ...
Cancer is the second leading cause of death in the U.S., claiming around 600,000 lives in 2022 alone. A diagnosis can be devastating, as the disease can often resist treatment and spreads ...
Esophageal squamous cell carcinoma (ESCC) is a highly aggressive malignancy with poor prognosis, and understanding the molecular mechanisms underlying its progression is crucial for developing ...
In a recent study reported in Nature Communications, scientists from The Jackson Laboratory (JAX) and UConn Health not only show how cancer hijacks this tightly regulated splicing and rearranging of ...
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Researchers discovered how to turn on cancer’s 'kill switch'
Cells have a natural editing system that allows them to rearrange genetic instructions to create different proteins from the ...
Alternative RNA splicing is similar to a movie editor cutting and rearranging scenes from the same video to produce distinct versions of a film. By deciding which sequences to keep and which to cut, ...
Alternative RNA splicing is like a movie editor cutting and rearranging scenes from the same footage to create different versions of a film. By selecting which scenes to keep and which to leave out, ...
On some level, biology is all about regulation, regulation, regulation. One way that our cells regulate their genes is through a process called alternative splicing, which entails the selective ...
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